Urinary Infections in the Elderly: Profile of Antibiotic Sensitivity from a Multicenter Study in Niamey (Niger)

UTI is one of common infectious for which empirical antibiotics are prescribed in elderly without evidence. It occurs antibiotic resistance and its increasing in health public. The purpose of the study was to determine the sensitivity and resistance of drug face to some antibiotic in the elderly in Niamey through a multicenter study.

Material and Methods: This is a descriptive cross-sectional study carried out over a period of 3 months from June 1 to August 31, 2022. The study population consisted of all the urine samples collected at the laboratories of the three major hospitals of Niamey for cytobacteriological urine exam.

Results: Of 3757 samples, 110 (2.4%) were at least 60 years old. The average age was 70.8 years with standard deviation 7.4 and extremes of 60 and 93 years. The predominance is male in 77.3% with a majority external exam sent (83.6%). Escherichia coli and Klebsiella spp were the species frequently isolated. According to the antibiogram, the enterobacteria were sensitivity for fosfomycin, imipenem and amikacin while they were resistant for levofloxacin, Amoxicillin clavulanic- acid and cephalosporin. E coli is sensitive for nitrofuran and Fosfomycin, resistance for ciprofloxacin, amoxicillin-clavulanic-acid and ceftriaxone. Klebsiella was sensitive for nitrofuran, cefixime, imipenem and resistant for AMC and ciprofloxacin.

Conclusion: The enterobacteria were sensitive for drug unusually use and expensive while the classic antibiotic became resistant little by little.

Key words: UTIs, Elderly, Antibiotics, Sensitive-resistance, Niger.